The idea of responsibility is deeply embedded into the “lifeworld” of human beings and not subject to change. However, the empirical circumstances in which we act and ascribe responsibility to one another are subject to change. Science and technology play a great part in this transformation process. Therefore, it is important for us to rethink the idea, the role and the normative standards behind responsibility in a world that is constantly being transformed under the influence of scientific and technological progress. This volume is a contribution to that joint societal effort.